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Registration Number

0215U006295, 0114U001022 , R & D reports

Title

To study the role of viral pathogens in the course of chronic bronchitis for optimizing the diagnosis, treatment and prevention of infectious acute attack of this disease

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Head

Dziublyk Oleksandr, Доктор медичних наук

Registration Date

05-01-2016

Organization

SO "National institute of phthisiology and pulmonology named after F. G. Yanovsky NAMS of Ukraine"

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Object - 121 patients with infectious exacerbation (IE) of chronic bronchitis (CB), 35 virus strains, 21 strains of bacteria. Aim - to increase the effectiveness of treatment of patients with viral IE CB by optimizing the use of diagnostic and drugs with antiviral activity. Methods - clinical, functional, microbiological, statistics. Improved the diagnostic scheme of IE HB by determining the level of C-reactive protein serum. New data on the spectrum of pathogens IE HB was obtained – at 43.7% of the patients identified viral pathogens, from 31.4% - bacterial. Developed the scheme of treatment of patients with IE HB through the use of inhaled decametoxine that reduce the intensity and duration (on 1–2 days) of symptoms of IE and reduced duration of antibiotic therapy, in combination with the drug L-arginine aspartate – reduced duration of IO on 2,4 days due to positive changes of free radical peroxidation of lipids. Sphere of application – pulmonology

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Гришило Антон Павлович
Гуменюк Микола Іванович
Денисова Ольга Василівна
Дзюблик Ірина Володимирівна
Дзюблик Олександр Ярославович
Капітан Георгій Борисович
Мокрицька Неоніла Анатоліївна
Мухін Олександр Олександрович
Недлінська Ніна Миколаївна
Обертинська Оксана Володимирівна
Сухін Ростислав Євгенович
Чечель Лариса Вікторівна
Юдіна Людмила Володимірівна
Ячник Віталій Анатолійович

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2020-04-02