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Information × Registration Number 0216U001465, 0115U000808 , R & D reports Title Improve tactics indications and treatment of patients with locally advanced and metastatic bladder cancer popup.stage_title Head Stakhovskyy Eduard Oleksandrovich, Registration Date 16-02-2016 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 The object of study - 137 patients with locally advanced and metastatic bladder cancer.Objective -pidvyschyty level of medical and social rehabilitation and quality of life of patients with locally advanced and metastatic bladder cancer by improving the evidence and determine the effectiveness of surgical tactics in treatment.Methods: clinical, laboratory, radiation, statistics.ANALYSIS OF locally advanced and metastatic RSM showed violations of urodynamics in the upper urinary tract in 37% of patients, which manifested itself ureterohydronephrosis and art - 16%; Article II. - 31%; III - 28%; Fourth century. - 18%; and V century. - 7%.Found that the specificity of CT in the diagnosis of secondary lesions of the lymph nodes is 64%, which is not enough for accurate verification on clinical diagnosis stage and demonstrates the need for routine pelvic limadenektomiyi during cystectomy in patients with PCM.The main pathological features of locally advanced and metastatic PCM is a high proportion (58.4%) poorly perehidnoklitynnyoho forms of cancer and high percentage (32.9%) squamous and mixed forms.Analysis of clinical material showed that 20.4% of patients with stage T2 RSM had regional or distant metastasis, which is the argument in favor of early radical treatment.It is proved that the complex pre- intra- and postoperative events multimodal program "fast-track surgery" in patients after radical cystectomy RSM, which is an excellent point perineal drainage and early activation of patients, thus reducing postoperative hospital stay (under 5, 4 ± 1,5) (p <0.0005).Found that of tsytoreduktyvnoyi cystectomy improves the quality of life of patients compared with PCT due to decrease pain (57,1 ± 13,5) and (47,7 ± 17,0), respectively (p <0.05) and increase indicators of mental health patients (64,7 ± 17,8) and (50,2 ± 14,7), respectively (p <0.05).Results of research introduced at the National Cancer Institute, Odessa Regional Clinical Oncology Center, Lviv State Oncological Medical - Diagnostic Center.Forward assumptions about the object of study - the definition of indications, techniques and operational requirements tsytoreduktyvnoyi cystectomy in locally advanced and metastatic bladder cancer. Product Description popup.authors Вітрук Юрій Васильович Войленко Олег Анатолійович Вукалович Петро Семенович Гаврилюк Оксана Миколаївна Катріченко Мирослава Олегівна Кононенко Олексій Анатолійович Лісний Іван Іванович Литвиненко Роман Анатолійович Пікуль Максим Валентинович Стаховський Едуард Олександрович Стаховський Олександр Едуардович Чепурнатий Михайло Володимирович popup.nrat_date 2020-04-02 Close