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Registration Number

0216U003414, 0113U000151 , R & D reports

Title

Еxplore the mechanism forming early disorders of the cardiovascular system in healthy primary school children.

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Head

Kvashnina L.V.,

Registration Date

27-01-2016

Organization

State organization "Institute of pediatrics, obstetrics and gynecology NAMS of Ukraine"

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The aim of the scientific study - to keep and improve a state of health of children of school age by development and deployment of methods of early diagnostics, prevention and correction of cardiovascular disorders. The 322 children of younger school age of 6-9 years in Kiev were under the supervision. Research methods - clinical, biochemical, instrumentalny, mathematical and statistical. On the basis of the analysis of a condition of system of lipid peroxidation/antioxidant defense, a lipidic and nitrogenous exchange, indicators of endotelialny function mechanisms of formation of early disorders cardiovascular systems at healthy children of school age and children with a syndrome of vegetative dysfunctions are defined. Schemes of the pharmacological differentiated and personalized correction of the revealed disorders with use of preparations of metabolic action of raznonaprvlenny influence are developed, approved and introduced. Novelty and relevance of researches consists in the establishment of features of system multiparametrical relationship of components of lipidic, nitrogenous balance, system of lipid peroxidation/antioxidant defense and indicators characterizing a condition of function vascular an endoteliya at healthy children and children with a syndrome of vegetative dysfunctions and development on this basis differentiated and the personalized of schemes of pharmacological correction of the revealed violations. By comparison the biochemical of the indicators characterizing endotelialny function and indicators of tripleksny ultrasonic a method and researches, revealed informational content of ultrasonic indicators that it is proved and confirmed by carrying out the linear correlation analysis.

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Ігнатова Т.Б.
Антоненко Л.В.
Апуховська Л.І.
Квашніна Л.В.
Клименко О.П.
Кравченко О.М.
Кузюк Л.Г.
Людвик Т.А.
Маковська Ю.А.
Матвієнко І.М.
Нікіфорова Т.М.
Родіонов В.П.

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2020-04-02