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Registration Number

0216U005547, 0113U000866 , R & D reports

Title

Influence of physical and chemical factors on ion-transport and antioxidant systems of bioobjects

Head

Sanagursky Dmytro Inanovych,

Registration Date

03-02-2016

Organization

Ivan Franko National University of Lviv

Description

It was established that amide derivatives penetrate the membrane peryvitelinovyy and the plasma membrane blastomeres. It was researched that medium concentrations of 10-3-10-5 M analyzed amide derivatives show embryotoxic properties, cause deceleration and abnormal development and further lead to expressed morphological changes in loach larvae. It has been established that the entire enzyme functional activity arises on 13th-15th minute of enzyme reaction, whereas increase in incubation duration of embryo membranes leads to the plateau-like curve formation of enzymatic ATP hydrolysis by incubation time with the maximum of ATPase activity on 14th-16th min of incubation. Investigational influence of sodium hypochlorite on content of TBA-active products and activity of enzymes of the antioxidant system, namely superoxide dismutase, catalase, glutationperoxydase in the lungs of bird. It is set that sodium hypochlorite by a concentration 5 µg/l predetermines the lowering of content of TBA-active products during 14 twenty-four hours in tissues of lungs, while sodium hypochlorite by a concentration 10 µg/l causes the lowering of their content only on 7th time of experience. It is shown that for the actions of sodium hypochlorite activity of superoxide dismutase slump below control values. Lipid peroxidation processes is increased in the spleen of chickens under influence of sodium hypochlorite in concentration 5 mg/l during 14 days. It was found that histamine interrupte the prooxidant state of the blood plasma, heart, liver and kidney.

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Бура Марта Володимирівна
Галан Марія Богданівна
Гарасим Наталія Петрівна
Генега Анастасія Богданівна
Дика Марія Василівна
Отчич Віра Петрівна
Санагурський Дмитро Іванович
Тарновська Антоніна Володимирівна