Search academic texts

Registration Number

0216U005571, 0115U003716 , R & D reports

Title

Plasmon sensing for high-sensitive diagnostics of ultra-small quantity of chemical matters and biomolecules..The second year of implementation

Head

Strelchuk V. Dmitrenko O. Ivanov,

Registration Date

03-02-2016

Organization

Department for special training National academy of science of Ukraine at Kiev University

Description

As the result of the project implementation, the original method for preparation of the effective nanostructured SERS-enhancing surfaces with the functionalized metallic nanoparticles, rough surfaces and island-like films of metals of Au and Ag were proposed. The investigation of effectiveness of obtained SERS-substrates with metallic nanoparticles depend on the technical conditions of their preparation were performed. The parameters of the SERS-active substrates and experimental conditions of detection of extrasmall quantities of the chemical matters (Rhodamine 6G) and biological molecules (glucose, DNA, tumor cells) were optimized. The correlation between the effectiveness of the analytical response and the optical, structural and morphological properties of the nanostructured SERS-substrates and the methods of their functionalization were found. The differences in the vibrational spectra of the standard tumor cells and the cells, treated with the gold nanoparticles as the changes of the frequencies and the intensities of the different spectral regions (proteins, nuclear acids, lipids) were registered and analyzed.?

Product Description

popup.authors

Бойко Микола Іванович
Дмитренко О.П.
Коломис Олександр Федорович,
Куліш Микола Полікарпович
Ніколенко Андрій Сергійович
Насєка Юрій Миколайович
Павленко Олена Леонідівна,
Романюк Артем Сергійович
Стрельчук В.В.
Стубров Юрій Юрійович