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Information × Registration Number 0216U006199, 0111U006142 , R & D reports Title Examine the molecular-biological mechanisms of yeast biomass influence on intestinal microbocenosis of animals and to develop scientific bases to use yeast containing probiotics in livestock farming. popup.stage_title Head Stefanyshyn Olha, Registration Date 16-02-2016 Organization Institute of animal biology Ukrainian academy of agrarion popup.description2 The optimum conditions mutahenizatsiyi yeast P. rhodozyma IBM Y-17268 nitrosoguanidine and the mutants-received collection overproducers carotenoids. Performance is best selected strains of 3.5 - 4.3 mg carotenoid / l medium. Addition of citric acid to the nutrient medium at a concentration of 1 g / l and 1.5 g / L has no effect on the growth of culture, but increases carotenogenesis yeast P. rhodozyma KNH1. The presence of corn oil in a medium for the cultivation and productivity increases carotenogenesis yeast P. rhodozyma NRRL Y - 17268, but does not affect the performance of mutant strains of the yeast P. rhodozyma with high content of carotenoids. Autoclaving process can be used to get the cell walls of yeast Phaffia rhodozyma, as one of the cheapest methods. It was established that four-day culture of Phaffia rhodozyma yeast cell disruption is 99.7% at 30 Hz mode for 30 min and 99.9% for 1 hour. For 5-day culture established cell disruption 99,6 ± 0,02% for the regime 37-37,8 Hz for 60 min. For the 6-day culture optimal for destruction biomass (99.96%) is 39 Hz mode within 45 minutes. The positive effect in terms of combined application of antibiotic drug supplements to the diet of yeast Phaffia rhodozyma the correction of dysbiosis in experimental composition mikrobotsenozu cecum quails. It was shown to increase the number of E. coli strains due to normal enzymatic activity, reducing the number strepto and staphylococci and fungi of the genus Candida displacement and against the content of the intestine. The result of the application of the scheme voiced biomass karotynosyntezuvalnyh yeast P. rhodozyma NGC-1 together with the antibiotic drug for 7 days. Product Description popup.authors Камінська Марта Володимирівна Понкало Леся Ігорівна Попик Ірина Миколаївна popup.nrat_date 2020-04-02 Close