Registration Number
0216U006576,
0113U001735
, R & D reports
Title
To detect the possibility of tularemia natural foci activity eveluation and epidemical complication forcast on the base genotype structure detection of F.tularensis strains that circulate in different regions of Ukraine
popup.stage_title
Head
Nekhoroshykh Zoya,
Registration Date
05-04-2016
Organization
Ukrainian Mechnikov Research antiplague institute
popup.description2
For the first time in Ukraine molecular-genetic investigation of 197 strains of F. tularensis holarctica was conducted on the base of MLVA, their genetic diversity was detected, 44 genotypes were identified (common, long-persistent, unique), their characteristic territorial spread was shown, genetic passports of individual strains were constructed. For the first time experimentally in vitro and in vivo phenotypic characteristics of natural F. tularensis isolates were studied that allowed to detect difference of their pathogen and adhesive properties. For the first time in Ukraine national multiplex PCR test-system was developed for indication and identification F. tularensis. The system does express-diagnostics of tularemia and in time correct treatment. Developed system was approbated. Technical documents were developed.
Product Description
popup.authors
Галаев А. В.
Джуртубаева Г. Н.
Егорова Е. А.
Ковбасюк Е. В.
Маньковская Н. Н.
Нехороших З. Н.
Пархоменко Н. Б.
Пилипенко Н. В.
Процышина Н. М.
Сахно Е. И.
popup.nrat_date
2020-04-02
