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Information × Registration Number 0217U006332, 0115U003159 , R & D reports Title New synthetic creation methods of nitrogen and sulphurcontaining biologicaly active compounds. popup.stage_title Head Markov Victor Ivanovich, Registration Date 27-03-2017 Organization State higher educational entity "Ukrainian State University of Chemical Technology" popup.description2 The object of study - salt N- (1-pyridinium) -N-alkoxy and N-acyloxy-N-chlorobenzamide; new 1,2,4-triazoles and measurement of the redox potential; the synthesis of bifunctional nitrogen derivatives. The purpose of the study – development of chemical libraries multipurpose azaheterocycles for the pharmaceutical field and the study of the scope of the transformations; development of scientific bases of formation of new catalysts and available environmentally sound methods of selective synthesis of bifunctional nitrogen compounds by the reactions of hydro- s degidroaminrovaniya monoethers of glycols; the expansion of a number of derivatives of 1- (N-alkoxy) aminopyridinium and further study their structure. Research methods – chemical synthesis, a thin layer chromatography (TLC), the Raystructure analysis (RSA), infrared spectroscopy (IR) and the nuclear magnetic resonance (NMR) - spectroscopy, mass spectrometry, quantum-chemical calculations. It is found that the lowering of the inversion of the barrier at the transition to the N-alkyl-N-isoelectronic sulfenyliminov; We developed a method for the preparation of azoles by N, S-alpha-amidoalkyl derivatives and other related reagents; development of technique og the synthesis new derivatives of 1,2,4-triazoles; method of synthesis butylamines dominated dibutylamines. The features of cyclization of threeazines to 1,3,5-substitions 1,2,4-threeazoles was investigated; widening series of derivatives of 1- (N-alkoxy) aminopyridinium and generalization of their structural features. It established the advantage in productivity of 2-etoxyethylamines nickel catalysts to contacts on other media. Branch of use of results of work – C 20.20 production pesticides and other agrochemical production, C 21.10 production of the main pharmaceutical products. Product Description popup.authors Білов Вододимир Вітальйович Бурмістров Константин Сергійович Варениченко Світана Анатоліївна Загорулько Сергій Павлович Задорожній Павло Вікторович Залізна (Велика) Катерина Володимирівна Карпіщенко Людмила Сергіївна Кисельов Вадим Віталійович Коломейцев Дмитро Олегович Куцик-Савченко Наталія Вікторівна Марков Віктор Іванович Мурашевич Богдан Валерійович Парамонова Тетяна Григорівна Покотило Ігор Олександрович Просяник Олександр Васильович Руденко Євген Олександрович Сова Світлана Борисівна Торопін Микола Васильович Харченко Олександр Васильович Штамбург Віктор Васильович Штамбург Василій Георгійович popup.nrat_date 2020-04-02 Close