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Information × Registration Number 0218U000391, 0117U001049 , R & D reports Title Development of algorithms individualization intensive care tactics in cancer patients multiorgan after operations popup.stage_title Head Krasnoselskyi M.V., Доктор медичних наук Registration Date 26-01-2018 Organization State Organization "Grigoriev Institute for Medical Radiologiy of the National Academy of Medical Sciences of Ukraine" popup.description2 Object of the study: postoperative complications in patients with multiple organ surgical interventions. The aim of the study was: to reduce the risk of postoperative complications in patients with multi-organ operations by individualizing the tactics of intensive care. Methods of research and equipment: clinical-instrumental, biochemical, clinical, statistical; Hyaco cardiac monitor, ultrasound diagnostic apparatus, electrocardiography apparatus. Theoretical and practical results: the disturbance of cardihaemodynamics in the early postoperative period proceeds wavyly with periods of ascent and oppression of the circulation. It is proved that in the treatment of patients after multiorgan operations, one should strive for blood circulation of normo or hyperdynamic type.The presence of enteral insufficiency syndrome in patients operated on the organs of the thorax and mediastinum is explained by the violation of blood circulation during the operation, hypoxia, which led to the appearance of intestinal insufficiency. A method for the early diagnosis of chronic cerebral ischemia in the syndrome of the inferior vena cava in cancer patients has been developed, including the determination of the level of neuron-specific enolase, glycolysis markers (glycerol-3-phosphate dehydrogenase and glyceraldehyde-3-phosphate dehydrogenase) prior to surgery. Novelty: the prognostic significance of changes in the concentration of neuron-specific enolase and enzyme enolase in blood serum in oncological patients with upper vena cava syndrome in the first 24 hours after surgery and the absence of their normalization for 3 days was estimated. The new scientific data on the adaptive capacity in oncological patients before and after multiorgan operations on the level of stress markers-cortisol, insulin and their ratio, are obtained. Efficiency of introduction: improvement of intensive care methods in cancer patients after multiorgan operative interventions allows to reduce the incidence of complications and the degree of lethality. The field of application: oncology, intensive care. Product Description popup.authors Дашкова С.О. Калініч С.Н. Колпакова Л.К. Красносельський М.В. Крутько Є.М. Мітряєва Н.А. Мазник Н.О. Пилипенко С.А. Сипко Т.С. Ткаченко А.А. popup.nrat_date 2020-04-02 Close