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Information × Registration Number 0218U000439, 0115U000271 , R & D reports Title To study the influence of fatty-acid contents of edible fats upon the state of tissues of oral cavity, liver and gastrointestinal tract and to elaborate the recommendations on fat consumption popup.stage_title Head Levitsky Anatoly Pavlovich, Registration Date 29-01-2018 Organization Odessa Scientific Research Institute of Stomatology popup.description2 The research objects are a liver, serum of rats, food fats, "Liposan", "Lekvin", "Olivka". The purpose of work is research of influence of fatty acids in composition different food fats on consisting of fabrics of the digestive system of norm and at experimental pathology, to offer the methods of correction of violations of lipid metabolism. Research methods - experimental, biochemical and statistical. Scientific novelty. 1) It is set that protracted the uses of surplus of food fats are caused by the increase of mass of body of rats, increase content of fat in a liver and in the serum, content of cholesterol in a serum, and also development of non-alcoholic steatohepatitis. The set violations in a greater degree showed up after introduction of palm and creamy butter, that was foundation to consider palmitic acid an important pathogenic factor. 2) It is experimentally rotined that the alimentary loading fats considerably reduces maintenance of irreplaceable fat acids. It is assumed that there can one of factors be oppressing of own biosynthesis of polyunsaturated of fatty acids and development avitaminosis of F in the mechanism of pathogenic action of surplus of fats. 3) Experimental dysbiosis on a background a high-fatty ration plays a subzero role in development of stomatological pathology (inflammation, decline of antioxydante defence, strengthening of recession. 4) The fixed facts were theoretical foundation for development of preparation of irreplaceable fatty acids of "Liposan" and additions of dietary "Lekvin" with maintenance of lecithin and quertulyne for the correction of lipid metabolism and prophylaxis of inflammatory and dysbiosis processes at the alimentary fatty loading, and also it is recommended to substitute in a ration ordinary sunflower-seed oil by a high-oleic acid "Olivka". Practical value. A normative-technical document is developed, permission of Ministery of health defence of Ukraine is got on application and the industrial issue of preparation of irreplaceable fatty acids of "Liposan" is organized for a dietary feed, "Additions of dietary "Lekvin" with maintenance of lecithin and quertulyne and high-oleic acid oil "Olivka" for a dietary feed. FATTY ACIDS CONTENTS of FATS, FABRICS of CAVITY of MOUTH, LIVER, DISBIOSIS, INFLAMMATION, IRREPLACEABLE FATTY ACIDS, HIGH-OLEIC ACID OIL Product Description popup.authors Васюк Валентина Леонідівна Демьяненко Світлана Олександрівна Кнава Ольга Едуардівна Левченко Олена Михайлівна Макаренко Ольга Анатоліївна Почтар Вікторія Миколаївна Севостьянова Тетяна Олександрівна Селіванська Ірина Олександрівна Ткачук Віталій Васильович Ходаков Ігор Володимирович Хромагіна Лариса Миколаївна Цушко Ілона Олександрівна popup.nrat_date 2020-04-02 Close