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Information × Registration Number 0218U000666, 0115U003159 , R & D reports Title New synthetic creation methods of nitrogen and sulphurcontaining biologicaly active compounds. popup.stage_title Head Markov Victor Ivanovich, Registration Date 07-02-2018 Organization State higher educational entity "Ukrainian State University of Chemical Technology" popup.description2 Object of research - derivatives of N-hetaryl-2,2-dichloroacetamidines; N-sulfenyl-, N-sulfinyl-, N-sulfonylimines of 2,6-di-tert-butyl-1,4-benzoquinone; xanthine phosphors, Cu (Zn) containing catalysts, aralazine 1,4-benzoquinone. The purpose of the work is to develop synthetic strategies for the generation of molecular diversity of nitrogen-containing heterocycles and to develop selective methods for controlling such processes. Conducting a study of possible types of biological activity among synthesized compounds. Methods of investigation - chemical synthesis, thin-layer chromatography (TLC), X-ray diffraction (PCA), infrared spectroscopy (IR), and nuclear magnetic resonance (NMR) -spectroscopy, ultraviolet spectroscopy (UV-), mass spectrometry and quantum-chemical calculations. It was established by molecular docking that N-hetaryl-2,2-dichloroacetamidines are a promising class of substances with potential anti-tuberculosis activity. The new method synthesized form derivatives of xanthians and benzopyrans that exhibit fluorescence in solutions with high quantum yields. Developed: method of synthesis of new fluorescent materials under the influence of Wilsmeier reagent; Vapor-phase method of obtaining 2- (N, N-dialkylamino) -ethyl amines on new catalysts; a method for the preparation of N- (2-ethoxyethyl) -piperidine. Branch of use of results of NIR – C 20.20 production pesticides and other agrochemical production, C 21.10 production of the main pharmaceutical products. Product Description popup.authors Білов Вододимир Вітальйович Бурмістров Константин Сергійович Варениченко Світана Анатоліївна Задорожній Павло Вікторович Залізна (Велика) Катерина Володимирівна Карпіщенко Людмила Сергіївна Кисельов Вадим Віталійович Коломєйцев Дмитро Олегович Куцик-Савченко Наталія Вікторівна Марков Віктор Іванович Мурашевич Богдан Валерійович Парамонова Тетяна Григорівна Просяник Олександр Васильович Руденко Євген Олександрович Сова Світлана Борисівна Торопін Микола Васильович Харченко Олександр Васильович Штамбург Віктор Васильович Штамбург Василій Георгійович Ященко Тетяна Борисівна popup.nrat_date 2020-04-02 Close