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Information × Registration Number 0218U001013, 0116U004828 , R & D reports Title Preclinical toxicity studies of melanin-substance for new medicinal preparations and efficiency of dermatotropic preparations on the basis of nanoparticals popup.stage_title Head Beregova Tetyana, Registration Date 10-01-2018 Organization Taras Shevchenko Kiev University popup.description2 The object of the study is the morpho-functional condition of the skin in rats after burn and wounds and the restoration of their characteristics after application of the proposed dermatotropic preparations based on nanoparticles of melanin, cerium dioxide and nanocomposite with fenugreek. The purpose of the work is to conduct a study of the effectiveness of dermatotropic drugs based on nanoparticles. The following methods were used to perform the work: pathophysiological, physiological, morphological, biochemical, microbiological, and molecular. The dependence of dermatotropic action of melanin, cerium dioxide and nanocomposite with fenugreek on their concentration in the proposed preparations was established and the mechanism of their dermatotropic action was established. Product Description popup.authors Іщук Т.В. Акуленко Т.В. Александров А.В. Берегова Т.В. Бучацький Л.П. Гаділія О.П. Голоборотько Є.Є. Давиденко А.В. Дворшенко К.О. Драницина А.С. Кабанов О.В. Караман Г.С. Карпенко Н.І. Коваль Т.В. Кондратюк Т.О. Кравченко О.С. Медведева Н.С. Нікітіна Н.С. Огородник Л.Є. Прибитько І.Ю. Присяжнюк А.І. Ракша Н.Г. Степанова Л.І. Торгало Є.О. Шквіра Г.О. popup.nrat_date 2020-04-02 Close