Registration Number
0218U006549,
0118U000357
, R & D reports
Title
Epidemiology, pathogenesis and clinical manifestations of Lyme disease (borreliosis) in its endemic regions of Ukraine, including Ternopil region; improvement of its diagnosis, treatment, rehabilitation and prevention.
popup.stage_title
Head
Andreychyn Mykhaylo,
Registration Date
06-06-2018
Organization
Horbachevsky Ternopil State Medical Academy
popup.description2
STUDY OF THE EPIDEMIOLOGY, PATHOGENESIS AND CLINICS OF LAME-BORELIOSIS IN THE ENDEMIC REGIONS OF UKRAINE, INCLUDING THE NUMBER IN THE TERNOPIL REGION, AND IMPROVING ITS DIAGNOSTICS, THERAPIES, REHABILITATION MEASURES AND PREVENTION. Object of research - workers of forest enterprises of Ternopil, Zhytomyr and Transcarpathian regions; students of the Ternopil National Pedagogical University named after. V. Hnatyuk, Ternopil National Polytechnic University. I. Puluj and the Ternopil State Medical University named after. AND I. Gorbachevsky; schoolchildren, members of the youth scout organization "Plast"; Patients with Lime borreliosis with predominant skin and musculoskeletal disorders, patients with tuberculosis; Ixod mites, selected from patients and from the environment. The purpose of the work is to investigate the etiological structure of Lime borreliosis (B. afzelii, B. burgdorferi sensu stricto and B. garinii) from inhabitants of a number of regions of Ukraine; to study the features of clinical manifestations of Lyme borreliosis in patients with skin diseases, nervous, cardiovascular and musculoskeletal systems, and the frequency of acute and chronic infections in adults and children in different regions of Ukraine; to investigate the ixod mites of regions selected from humans and the environment for the infection with the major species B. burgdorferi and B. miyamotoi, A. phagocytophilum. Methods of research: clinical (physical, questionnaires); epidemiological; Laboratory (PCR: DNA of major species of Borrelia burgdorferi, Borrelia miyamotoi, Anaplasma phagocytophilum (in material from patients, in mites), ELISA: IgM and IgG antibodies to the major species of Borrelia burgdorferi in the material from patients: blood serum, synovial fluid, interleukins of different groups ; western blot method: IgM and IgG to the antigens of the major species Borrelia burgdorferi in serum of patients); thermography; statistical
Product Description
popup.authors
Андрейчин Михайло Антонович
Андрейчин Сергій Михайлович
Банадига Наталія Василівна
Васильєва Наталія Аврумівна
Верещагіна Наталія Ярославівна
Галіяш Наталія Богданівна
Грищук Леонід Андрійович
Климнюк Сергій Іванович
Копча Василь Степанович
Марчук Ольга Михайлівна
Никитюк Світлана Олексіівна
Павлишин Галина Андріївна
Подобівський Степан Степанович
Покришко Олена Володимирівна
Рогальський Ігор Олегович
Романюк Лідія Богданівна
Сміян Світлана Іванівна
Ткачук Наталія Іллівна
Федонюк Лариса Ярославівна
Шкільна Марія Іванівна
popup.nrat_date
2020-04-02