Registration Number
0219U003076,
0117U003488
, R & D reports
Title
Development of new technologies for integrated treatment of gastrointestinal tract tumors considering prognostic molecular tumor markers
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Head
Krasnoselskyi M.V., Доктор медичних наук
Registration Date
17-01-2019
Organization
Grigor'ev Institut for Medical Radiology
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Object of research: tumor diseases of the digestive tract. The purpose of the study is to increase the efficiency of complex treatment of patients with tumors of the digestive tract by individualizing on the basis of determining the features of molecular-biological indicators of the malignant process. Research methods and equipment: clinical-instrumental, immuno-enzymatic, electron-microscopic, dosimetric, statistical; hematologic analyzer Sysmex SF-3000, semi-automatic immunoassay analyzer Dynex DS2 Automated ELISA System Immunoassay Analyzer. Theoretical and practical results: specific features of molecular biological indicators of the malignant process were determined, the algorithm of an individualized choice of treatment scheme in radical and non-radically treated patients with oncopathology of the digestive tract was developed and substantiated. Novelty: for the first time, the technology of individualization of complex treatment of patients with tumors of the digestive tract was developed, which allowed to improve general and non-recurrent survival, evaluated the informative nature of biomarkers of different nature for prediction or prediction of the development of relapses and prolongation of the disease in cancer cases. The effectiveness of the implementation: individualization of the choice of tactics of complex treatment of cancer of the digestive tract, which contributes to reducing the frequency of relapses by 15%. The field of use is oncology, surgery.
Product Description
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Вербицький М.В.
Граматюк C.М.
Кондрашова О.І.
Красносельський М.В.
Мовчан О.В.
Підлісний Р.А.
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2020-04-02
