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Information × Registration Number 0219U003196, 0118U000243 , R & D reports Title Development of methodical recommendations for the use of chondroprotectors and multiprobiotics for correction of joint pathology. popup.stage_title Head Dvorshchenko Kateryna, Доктор біологічних наук Registration Date 28-01-2019 Organization Taras Shevchenko Kiev University popup.description2 The object of the study is the morpho-functional condition of the skin in rats after burn and wounds and the restoration of their characteristics after application of the proposed dermatotropic preparations based on nanoparticles of melanin, cerium dioxide and nanocomposite with fenugreek. The purpose of the work is to conduct a study of the effectiveness of dermatotropic drugs based on nanoparticles. The following methods were used to perform the work: pathophysiological, physiological, morphological, biochemical, microbiological, and molecular. Experimental pathologies of joints (monoiodacetate-induced arthrosis and collagen-induced arthritis) caused significant histological changes of the knee joints and the violations in the intensity of free radical processes, antioxidant system, markers of cartilage tissue metabolism, and genes expression of the cartilage tissue in rats. Product Description popup.authors Вовк А.А. Гайда Л.М. Дворшенко К.О. Драницина А.С. Коваль Т.В. Кот Л.І. Преображенська Т.Д. Фалалєєва Т.М. Шквира Г.О. popup.nrat_date 2020-04-02 Close