Registration Number
0219U003286,
0114U000108
, R & D reports
Title
Characteristics of perinatal pathology, immunopathological states and the influence of exogenous factors on the health and quality of life of children from different groups of risk
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Head
Korzhynsky Uriy Stepanovych,
Registration Date
06-02-2019
Organization
Danylo Halytsky Lviv National Medical University
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Delay in physical development is observed in 18.5% of young children who were in the neonatal period on prolonged mechanical ventilation. Early-age children who were on prolonged mechanical ventilation in the neonatal period and had fan-associated complications have lower body mass indexes compared to children who did not have complications of mechanical ventilation. Delay in neuropsychiatric development is observed in 11.8% of infants who were in the neonatal period on prolonged mechanical ventilation. In newborns with mechanical ventilation.in mode SIMV/PS, along with the activation of the system of LPO, decreased activity of AO compared with children on nCPAP, which increases the risk of different pathological conditions in this group of patients. High concentrations of oxygen (> 50%), high peak inspiratory pressure and, respectively, the mean pressure in the respiratory tract are associated with the activation of the LPO. The discrepancy between increased lipid peroxidation potential and decreased activity of AOP is associated with an increase in the duration of respiratory therapy in newborns. According to the results of the examination of the inoculum function of the PO, no child had diabetes mellitus and glucose intolerance. Almost 50% of children with excess body weight and pathological changes in the pancreas have found a pathological sugar curve, which may indicate a pre-nose degradation of the carbohydrate metabolism ("functional" changes). At the same time, the pathological sugar curve was almost twice as likely to be found in Hp (+) patients. For this, the important role is played by related risk factors, such as excess body weight and genetic predisposition to the development of diabetes mellitus. The level of C-peptide in almost a third of children in both groups slightly exceeded the reference values. In infants from an early age with a viral infection, the appointment of antibacterial therapy at elevated PCT levels accelerates the recovery process and facilitates its progress. At 4-5 days of treatment in all children of the main group there was a clinical recovery with normalization of defecation, while in the comparison group in these terms, clinical recovery occurred only in 80% of cases.The comparative characteristics of the complaints of children who were under surveillance for two months after the infection of the mouth of the mouth revealed that the removal of the main complaints during the period of reconvalescence in the children of the main group was observed already in the 1 st month of observation (appetite recovery, abdominal pain abnormal, normalization of function intestine), in the 2nd month of observation the function of the intestine completely restored.
Product Description
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Іванців-Гріга Ірина Степанівна
Винницька Олена Володимирівна
Дубей леонід Ярославович
Коцай Богдан Романович
Лісний Андрій Євстахійович
Маркін Андрій Ігорович
Марченко Тетяна Зіновіївна
Няньковська Олена Сергіївна
Омеляненко Ольга Василівна
Роговик Наталія Волдодимирівна
Савчак Наталія Євгенівна
Сакалош Леся петрівна
Слівінська Христина Богданівна
Томків Зоряна Володимирівна
Троцький Григорій Михайлович
Уська Віра Романівна
Чуйко Марія Миколаївна
Яцкевич Ірина Іванівна
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2020-04-02
