Registration Number
0219U003565,
0117U004979
, R & D reports
Title
Experimental substantiation of using carbon adsorbents for the treatment of extensive damages caused by external irradiation.
popup.stage_title
Head
Nikolaev Vladimir Grigorievich,
Registration Date
24-01-2019
Organization
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology
popup.description2
The model of acute radiation sickness of moderate severity in rats and the design of experiments with enterosorbent were developed. An enterosorbent and carbon nanoparticles were synthesized, and a preliminary study of their properties was performed. It has been proved that carbon nanoparticles possess adsorption activity and a high association rate with respect to the albumin molecule (K ass 3,3 x 107 M-1), and they are capable of causing conformational changes in the protein globule during interaction. It has been shown that the application of adsorptive carbon bandage in rats causes the reduction of the epithelialization period of skin damage after ultraviolet irradiation (1.7-fold) and burn injury of ІІ-ІІІА degree obtained on a background of general irradiation at a dose of 8 Gy (1.4-fold).
Product Description
popup.authors
Іванюк А.А.
Бардахівска К.І.
Геращенко Б.І.
Корнеєва Л.М.
Коротич В.Г.
Масленний В.М.
Ніколаєв В.Г.
Сарнацька В.В.
Сахно Л.О.
Сидоренко О.С.
Снєжкова Є.О.
Юшко Л.О.
popup.nrat_date
2020-04-02
