Registration Number
0219U004527,
0116U008934
, R & D reports
Title
Development of new curative and preventive means and reasoning for their usage in combination treatment of oral lesions under exogenous and endogenous factors of risk.
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Head
Kravchenko Ludmila Sergeevna,
Registration Date
03-09-2019
Organization
Odesa National Medical University
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Development of mean for the oral care rinse "Apifil" on the basis of biologically active matters of directed local action with anti-inflammatory, antimicrobial, wound-healing properties. The local therapy of periodontitis against a background of hyperpeptic gastritis at smoher patients resulted in correction of definite metabolic violation in the mouth liquid that consists in normalixing influence on processer of lipid peroxidation, inflammation and activation of the protective systems of oral cavity, accelerating removing harmful influence of damaging factors and restoring the state of periodontal tissue than using of traditional treatment. The results of the rapid urease test (RUT) on Helycobacter pylori with the material from the stomach and oral cavity were also analyzed and relationship between the positive reaction of RUT with gastric biopsy specimens and the reaction of RUT with material from the oral cavity as well as positive antimicrobial effect of new mean. The results of researches give reason to recommend the local therapy of the new mean for prevention of inflammatory processes in tissues of oral cavity and creation of optimal terms for the removal of the structural-functional violations caused by the endogenous and exogenous factors of risk.
Product Description
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Бас Олексій Андрійович
Золотухіна Олена Леонідівна
Кравченко Людмила Сергіївна
Щербаков Сергій Васильович
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2020-04-02
