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Registration Number

0219U004541, 0117U000669 , R & D reports

Title

Additional markers for assessing the state of hemostasis: the relationship with the prognosis and therapy of acute coronary syndromes

Head

Koval' Olena Akindynivna,

Registration Date

03-09-2019

Organization

State organization "Dnepropetrovsk medikal akademy of Ministry Health Ukraine"

Description

The study revealed a direct strong relationship between the level of free DNA and the count of leukocyte. It is proved that ischemic albumin can be used as an additional marker for assessing the level of coronal ischemia. It can be an integral marker for hospital and long term prognosis in patients with acute coronary syndrome (ACS). The free DNA-level is an additional independent marker of the inflammatory thrombotic response to myocardial damage in patients with ACS. It was found that the use of corvitin, doxycycline and eplerenone leads to the restoration of the heart state in rats with experimental myocardial ischemia. These medications can also reduce the negative manifestations of carbonyl-oxidative stress.

Product Description

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Гордієнко Юлія Анатоліївна
Коваль Олена Акіндинівна
Скоромна Анастасія Сергіївна
Ткаченко Вікторія Андріївна
Шаульська Ольга Едуардівна
Шевцова Алла Іванівна
Щукіна Олена Сергіївна