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Information × Registration Number 0219U005470, 0114U007007 , R & D reports Title Correction of endothelial dysfunction, oxide-reduction homeostasis and blood lipid spectrum in internal medicine practice. popup.stage_title Head Zolotariova Natalia Artemovna, Registration Date 26-11-2019 Organization Odesa National Medical University popup.description2 The analysis of the study of 289 patients with coronary heart disease; comorbid gout with hypertension. The purpose of the study was to improve the methods of therapeutic correction in patients with endothelial dysfunction, disorders of redox homeostasis and lipid metabolism, the introduction of the developed materials into clinical practice. Research methods: clinical, biochemical (markers of endothelial dysfunction in plasma), instrumental (endothelium dependent (FMD) and independent (NMD) vasodilation), statistics. In the complex treatment with the use of the cytoprotector Mexicor, the content of the main markers of lipid peroxidation significantly decreased, the activity of antioxidant enzymes decreased. Atorvastatin improves the clinical course of the disease ("soft" anti inflammatory action), significantly affects ED (VWF, ET 1) with an equivalent effect on IL 1 and FMD; rosuvastatin better improves plasma lipid profile and coagulation hemostasis. Product Description popup.authors Золотарьова Наталія Артемівна Ковалевська Людмила Андріївна Медянка Юрій Степанович Писковацький Павло Михайлович Романченко Максим Ігорович Селіванов Віктор Володимирович Соломко Олена Володимирівна popup.nrat_date 2020-04-02 Close