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Registration Number

0219U005474, 0114U007014 , R & D reports

Title

The search, development and aplication of the newest methods of prophylaxy and treatment of surgical and oncologic diseases of hepatopancreatoduodenal zone

Head

Zaporozhchenko Boris,

Registration Date

26-11-2019

Organization

Odesa National Medical University

Description

The object of the study - 121of patients with acute cholecystitis over the age of 60 years, 148 of patients with chronic pancreatitis, complicated by pseudocyst formation, and 275 of patients with focal lesions of the hepatopancreatoduodenal area, which were operated on in surgery department with miniinvasive surgical technologies. The aim of the study was to improve the results of complex surgical treatment of patients with diseases of the hepatopancreatoduodenal zone.Research methods - general clinical, laboratory (complete blood and urine tests, biochemical test, blood glucose, total bilirubin and its fractions, activity of aminotransferases - ALT and AsAT, urea, creatinine, determination of the state of immunological reactivity by cellular and humoral indices of blood, the state of lipid peroxidation and the state of antioxidant protection according to thiol-disulfide and ascorbate redox systems data) and instrumental methods (CT, MRI, ultrasound, FEGDS). The improvement of general clinical parameters, the dynamics of the functional state of the pancreas, immunological reactivity, the blood coagulation system and the system of lipid peroxidation monitoring in the conditions of the of minimally invasive surgical technology comparing to traditional surgical treatment has been established.

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Бородаєв Ігор Євгенович
Горбунов Анатолій Анатолійович
Запорожченко Борис Сергійович
Качанов Валерій Миколайович
Колодій Валентин Валентинович
Муравйов Петро Тадеушович
Шарапов Ігор Володимирович
Шевченко Валерія Генадіївна