Registration Number
0219U100838,
0118U002319
, R & D reports
Title
Search and Analysis of Micro RNA Involved in Osteogenic Differentiation of Mesenchymal Stem Cells for the Purpose of Their Application in the Development of Bone Marrow Implants
popup.stage_title
Head
Matsevych Larysa L.,
Registration Date
22-03-2019
Organization
Institute of Molecular Biology and Genetics of NAS of Ukraine
popup.description2
Meta-analysis of existing experimental data concerning miRs involved in regulation of stem cells status and differentiation process was performed. Possible connections between miRNAs and MSC differentiation have been investigated. The involving of some human (let-7a, mir-101, mir-143, mir-26a, mir-29b, mir-21, mir-218, mir-17, mir-138, mir-222, mir-31) and rodent (mir-129-1-3p, mir-146a, mir-221, mir-30b, mir-30c) miRs in control of MSC osteogenic differentiation processes was confirmed. It was shown also that mir-23b can be used as marker of some pathological and age-related processes in human bone tissue.
Product Description
popup.authors
Balatskyi Volodymyr V.
Piven Oksana O.
Ruban Tetyana A.
popup.nrat_date
2020-04-02
