Analysis of the influence of different forms of calix  arenes on cell proliferation of different origin.
Garmanhuk Ludmila V., Доктор біологічних наук
Taras Shevchenko National University of Kyiv
Object of study: Proliferation rates of colon and gastric cancer tumor cells
Purpose: To determine the effect of different forms of calix  arenas on the proliferation of tumor cells of different origin
Research methods: methods of cell culture, determination of growth characteristics of tumor cells, morphological analysis.
The study found that the tested compounds of calix  arena C-145, when screened for colon and gastric cancer cells, showed an anti-proliferative effect and revealed a population redistribution in Colo 205 cells, which indicated an increase in the clastin fraction fraction; AGS gastric cancer cells did not change their morphological parameters; the nuclear cytoplasmic ratio remained flat in control without the addition of calix  arenas.