Analysis of the influence of different forms of calix [4] arenes on cell proliferation of different origin.
Head
Garmanhuk Ludmila V., Доктор біологічних наук
Registration Date
03-12-2019
Organization
Taras Shevchenko National University of Kyiv
Description
Object of study: Proliferation rates of colon and gastric cancer tumor cells
Purpose: To determine the effect of different forms of calix [4] arenas on the proliferation of tumor cells of different origin
Research methods: methods of cell culture, determination of growth characteristics of tumor cells, morphological analysis.
The study found that the tested compounds of calix [4] arena C-145, when screened for colon and gastric cancer cells, showed an anti-proliferative effect and revealed a population redistribution in Colo 205 cells, which indicated an increase in the clastin fraction fraction; AGS gastric cancer cells did not change their morphological parameters; the nuclear cytoplasmic ratio remained flat in control without the addition of calix [4] arenas.
Head: Garmanhuk Ludmila V.. Analysis of the influence of different forms of calix [4] arenes on cell proliferation of different origin..
Taras Shevchenko National University of Kyiv. № 0219U101945
