Registration Number
0220U001084,
0117U000419
, R & D reports
Title
"Development of modern technology for diagnosis and intensive treatment of infectious lesions of the nervous system."
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Head
Borshev Sergei,
Registration Date
22-01-2020
Organization
Киевский НИИ эпидемиологии и инфекционных болезней им. Л.В. Гpомашевского
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Report (final): pages - 140, tables - 16, figures - 4, sources - 45. Object of study: pathological process in 1200 Patients With inflammatory disease of the nervous system, who are on inpatient treatment in the intensive care and detoxification unit. Research methods: CLINICAL, biochemical, serological, molecular genetic, Instrumental, statistical. The most effective treatment regimens for viral mixed infection and viral bacterial therapy are complex therapies, which are based on the use of antiviral drugs, taking into account the etiology of the process in combination with discrete plasmapheresis and intrathecal administration of dexamethasone. In viral infection, a good effect is observed in 65.99% of cases, viral and bacterial - 89.69% of cases. The authors propose a two-stage algorithm for laboratory examination of patients with Nervous system lesions, with the determination of ITS Total IgG and M, specific Antibodies (IgG) in the cerebrospinal fluid, aimed at differential diagnosis between infectious and autoimmune diseases, and treatment of patients with non-inflammatory disease. For the first time in Ukraine, intrathecal administration of dexamethasone is recommended to counteract local inflammatory reactions in the central nervous system and stabilize BBB. Methodological documents, standards - 15, diagnostic methods - 1, treatment - 14. Developed 3 theses. Conducted scientific seminars - 4, reports - 25. Published 5 articles (1 abroad), abstracts - 14. Accepted for publication 2 articles.
Product Description
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Борщев С.П.
Говорова Д.В.
Матяш В.І.
Панасюк Е.Л.
Парфенюк Ю.В.
Трембачева Н.С.
Фільчаков І.В.
Шагінян В.Р.
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2020-04-02
