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Information × Registration Number 0220U100294, 0117U002383 , R & D reports Title Molecular genetic features of adaptation of the cardiovascular system to the intense physical activities popup.stage_title Head Drozdovska Svitlana B., Registration Date 15-01-2020 Organization National University of Ukraine on Physical Education and Sport popup.description2  Key words: (5 – 6 words): myocardium hypertrophy, long noncoding RNA, genes polymorphisms, adaptation to physical exercises. Aim of study: to study the role of genes polymorphisms and non-coding RNA expression level in the molecular genetic mechanisms of adaptation and pathological processes in the myocardium during prolonged intensive physical exercises. Aim of the research stage: by silencing (interference) RNA gene DNA to establish the possibility of reducing the risk of pathologe of the myocardium under the influence of intense physical exercises. Research object: molecular genetic mechanisms of myocardial hypertrophy development in athletes under the influence of physical exertion Article of research: the establishment of the role of non-coding RNA and gene polymorphisms in the development of myocardial hypertrophy in response to intense physical loads of an aerobic nature and the possibility of correcting this link of molecular genetic mechanisms Methods of researches: molecular genetic (PCR, DNA isolation) and physiological (ECG, ultrasound) Product Description popup.authors Iliin Volodymyr M. Vinnychuk Yuliia D. Verbovets Nina F. Honcharov Serhii V. Dosenko Victor Ye. Polishchuk Anna O. Tron Ruslan A. Tumanovska Lesia V. Khmelnytska Yuliia K. popup.nrat_date 2020-04-02 Close