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Information × Registration Number 0220U100755, 0117U004270 , R & D reports Title To investigate the effectiveness of innovative methods of the experimental spinal cord and peripheral nerve restoration using tissue neuroengineering and electro-surgery technology. popup.stage_title Head Tsymbaliuk Vitalij I., Доктор медичних наук Registration Date 24-01-2020 Organization The State institution "Romodanov neurosurgery institute, National academy of medical sciences of Ukraine" popup.description2  In this study, data on the effectiveness of immediate filling of the adult rat's sciatic nerve defect with a collagen tubular conduit with neural crest stem cells are retained. The results indicate that there is no significant difference between the tissue-engineered tool and conventional autoneuroplasty; tested tool has significant potential for improvement and is characterized by significantly faster regeneration. Transplanted neural crest stem cells were differentiated into schwann cells and provided myelination of newly formed nerve fibers. Tested welded joint of the ends of the transsected sciatic nerve in some electroneuromyographic and morphometric parameters outperforms traditional neuroraphy. Implantation of a chitosan-based tunneling matrix into the spinal cord injury zone significantly impairs the regeneration process, potentiate post-traumatic spasticity. Product Description popup.authors Velichko Olga M. Veselova Olga I. Gridina Nina Ya. Draguntsova Natalia G. Medvedev Volodymyr V. Molotkovets Vitaliy Yu. Nakhaba Oleksandr O. Petriv Taras I. Senchyk Yurii Yu. Tatarchuk Mikhail M. Tsymbaliuk Vitaliy I. popup.nrat_date 2020-04-02 Close