Registration Number
0220U100844,
0115U002767
, R & D reports
Title
Clinical and experimental study on optimization of the methods of treatment of exo- and endotoxicosis.
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Head
Konovchuk Viktor M., Доктор медичних наук
Registration Date
28-01-2020
Organization
HSEE of Ukraine "Bukovinian State Medical University"
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A comparative evaluation of the APACHE II, SOFA, MODS scales was first carried out to assess grave condition of the patients in case of severe sepsis in the Chernivtsi region. For the first time, the study of the prognostic significance of the investigated scales under conditions of Resuscitation Department Intensive Care (RDIC) of the Regional Clinical Hospital (RCH), Chernivtsi was accomplished The equation of assessment of the severity of the patient's condition based on the level of molecular average mass (MAM) in the blood of patients with severe sepsis at RDIC admission was developed. The scale of estimation of polyorganic damages has been developed.
For the first time, the presence of dose-dependent changes in behavioral responses, the state of lipid peroxidation and oxidative modification of proteins in the blood and liver tissue of sexually mature rats with different types of acetylation under conditions of sub-acute influence of manganese chloride and lead acetate has been determined. For the first time, the efficacy of quercitin as an available preventive pathogenetically substantiated method in case of manganese chloride and lead acetate sub-acute toxicity in sexually mature rats with "fast" and "slow" types of acetylation has been demonstrated.
Product Description
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Akentiev Serhii O.
Andruschak Andrij V.
Bodnar Oleh B.
Vatamanesku Livii I.
Kalutskyi Ihor V.
Kyfiak Petro V.
Kovtun Anatoliy I.
Konovchuk Viktor M.
Levytska Svitlana A.
Mazur Olha O.
Petrynych Volodymyr V.
Plaksyvyi Oleksandr H.
Rotar Vasyl I.
Sapunkov Oleh D.
Sokolnyk Sergiі O.
Tkachuk Oleksii V.
Khashchuk Vasyl S.
Yakovets’ Karolina I.
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2020-04-02
