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Information × Registration Number 0220U101108, 0118U001193 , R & D reports Title New methodological approaches to pathogenetic treatment of dysfunction of the proximal nephron in terms of development disregulating the pathological process of renal and extrarenal origin popup.stage_title Head Rohovyy Yuriy Ye., Доктор медичних наук Registration Date 03-02-2020 Organization HSEE of Ukraine "Bukovinian State Medical University" popup.description2  The goal of the work. Development of new methods of treatment of dysfunction of the proximal nephron, syndrome of loss of sodium ions with urine, disorders of glomerular-tubular, tubular-tubular balance and tubulo-glomerular feedback under conditions of development of dysregulatory pathological process of renal pathology Methods of investigation: pathophysiological, biochemical, enzyme-linked immunosorbent, physiological, histo-enzymochemical, histological, morphometric, microbiological, statistical. Abstract. The report presents a theoretical generalization and new solution to the scientific problem of developing a new direction of diagnosis, treatment and prophylaxis of dysfunction of the proximal nephron, the syndrome of loss of sodium ions in relation to the development of dysregulation pathological process of renal and extrarenal complex, the use of microarray, alflorex, dospatalin, transfer of the factor "Edvensd". An effective correction of proximal nephron damage in irritable bowel syndrome by the preparation of alflorex is proposed, which leads to rupture of the formed large and small water circles and causes a more effective protective property of this drug in the correction of primary and secondary primary and secondary. Improved the efficiency of correction of proximal tubule dysfunction for irritable bowel syndrome by 30% by using alflorex. An effective method for the prevention of nephrolithiasis by the detection of kidney stones in radiographic examination one year after the application of methods of prevention of maintaining the daily diuresis value of not less than 2 l / 1,72 m2 with 95% for the known prototype to 100% using the proposed method (water consumption from ' high redox potential and low surface tension, which has been treated with coral calcium). Product Description popup.authors Doroshko Volodymyr A. Motruk Maria P. Olenovich Lyudmila V. Rohovyy Yuriy Ye. popup.nrat_date 2020-04-02 Close