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Information × Registration Number 0220U101398, 0117U006276 , R & D reports Title Development of new generation implants is based on synthetic bone tissue analogues and mesenchymal stem cells for bone tissue damage reconstruction. popup.stage_title Head Piven Oksana O., Кандидат біологічних наук Registration Date 10-02-2020 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description2  During the implementation of the scientific and technological project, the effect of bioactive ceramics containing calcium on the differential potential of MSCs was investigated. As a result, we have shown for the first time that the tested biocomposites induce an increase in the level of osteogenic differentiation of rat mesenchymal stem cells, as evidenced by an increase in the level of osteogenic differentiation markers Osteopontin, Osteocalcin, and positive red Alizarin. Moreover, the bioceramics of GTG-1 had a stronger effect on the induction of differentiation into osteoblasts, which allows the use of these granules in the creation of combined bone tissue implants. Product Description popup.authors Balatskyi Volodymyr V. Boriachuk Olena O. Macewicz Larysa L. Papuga Alexander Ye. Ruban Tetyana A. popup.nrat_date 2020-04-02 Close