Registration Number
0220U101398,
0117U006276
, R & D reports
Title
Development of new generation implants is based on synthetic bone tissue analogues and mesenchymal stem cells for bone tissue damage reconstruction.
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Head
Piven Oksana O., Кандидат біологічних наук
Registration Date
10-02-2020
Organization
Institute of Molecular Biology and Genetics of NAS of Ukraine
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During the implementation of the scientific and technological project, the effect of bioactive ceramics containing calcium on the differential potential of MSCs was investigated. As a result, we have shown for the first time that the tested biocomposites induce an increase in the level of osteogenic differentiation of rat mesenchymal stem cells, as evidenced by an increase in the level of osteogenic differentiation markers Osteopontin, Osteocalcin, and positive red Alizarin. Moreover, the bioceramics of GTG-1 had a stronger effect on the induction of differentiation into osteoblasts, which allows the use of these granules in the creation of combined bone tissue implants.
Product Description
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Balatskyi Volodymyr V.
Boriachuk Olena O.
Macewicz Larysa L.
Papuga Alexander Ye.
Ruban Tetyana A.
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2020-04-02
