Registration Number
0220U104249,
0120U104294
, R & D reports
Title
The influence of antiviral and thrombolytic drugs on the model membranes of viral particles and eukaryotic cells.
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Head
Dovbeshko Galyna I., д.ф.-м.н.
Registration Date
15-12-2020
Organization
Institute of Physics of National Academy of Sciences of Ukraine
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It was createdin silico model membrane with lipid composition and curvature like the SARS-CoV-2 virus membrane and the human lung epithelial cell membrane. It was performed simulation of spontaneous incorporation of ticagrelor and remdesivir into model membranes were created and the ability these membranes to aggregation was evaluated. An model membrane in vitro was created and the effect of surface curvature on lipid ordering was determined.
Product Description
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Yesylevskyy Semen O.
Barabash Yurii M.
Gnayuk Olena P
Dovbeshko Galyna I.
Olenchuk Maryna V.
Pyrshev Kyrylo O.
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2020-12-15