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Information × Registration Number 0220U104545, 0120U000181 , R & D reports Title Development of enzyme-linked immunosorbent assay systems using recombinant toxoid CRM197 for monitoring the level of antidiphtheria antibodies. popup.stage_title Head Komisarenko Serhiy Vasylovych, Доктор біологічних наук Registration Date 22-12-2020 Organization Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine popup.description2 Enzyme-linked immunosorbent assay using recombinant toxoid CRM197 to measure diphtheria antibodies level in human serum has been developed. This technique is tested on sera from peoples vaccinated against diphtheria. As a result of project, the prototype of immunoenzyme test-system for detecting the diphtheria toxin antibodies level in human was developed, and the technical specifications for the production of this immunoenzyme test-system were created. After introducing in production (Hema Ltd., Kyiv) the developed test-system can be used in mass screening studies of diphtheria immunity, as well as in clinical trials of new diphtheria vaccines.  Product Description popup.authors Galkin Oleksandr Yu. Katashinskaya Daryna O. Kolyba Denys V. Krynina Olha I. Kulyk Yaroslava S. Labintsev Andriy Yu. Romanyuk Svitlana I. Siromolot Andriy A. popup.nrat_date 2020-12-22 Close