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Information × Registration Number 0221U101489, 0116U001417 , R & D reports Title Theoretical and methodological investigation for treatment and prevention of prion infection through the creation of new generation drugs using nanotechnology. popup.stage_title Head Vlizlo Vasyl V, Registration Date 21-01-2021 Organization Institute of Animal Biology of NAAS popup.description2  A prototype of a drug for the treatment and prevention of prion infections based on the delivery of antisense oligodeoxynucleotides was developed. The prototype of the drug for the delivery of antisense oligodeoxynucleotides reduces the content of physiological prion in prion-replicating organs, does not cause the appearance of specific antibodies, is low-toxic and promising for the design of drugs for the treatment and prevention of prion infections. Utility model patent "The method of reducing of the cellular prion content in animals" (№ 144124, Bull. № 17) was obtained. Methodical recommendations "Methodology of creating and evaluating the efficiency of nanosized polymeric carriers with nucleic acids" have been developed and published Product Description popup.authors Ilkov Oleksandra O Kozak Mariya R Kuzmina Nataliia V Kushkevych Mariana Mikush Nataliia Yu. Martyn Yurii V Ostapiv Dmytro D Petruh Iryna M popup.nrat_date 2021-01-21 Close