Registration Number
0221U104624,
0120U101957
, R & D reports
Title
Synthesis of rhenium compounds with antioxidant and luminescent properties and research of their specific interaction with biological molecules.
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Head
Shtemenko Oleksandr V., Доктор хімічних наук
Registration Date
05-04-2021
Organization
Ukrainian State University of Chemical Technology
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The object of study - physico-chemical and biological properties compounds of Re(III) and Re(I). The aim of the work is the synthesis of starting materials and complex compounds Re(I) and Re(III). Research methods - preparative chemistry and physicochemical methods, electrical conductivity, electronic, nuclear magnetic resonance (NMR) and infrared (IR)-spectroscopy. It was investigated that the change of ligands, taking into account their properties, as well as the properties of the cluster center Re(III) and Re(I) contribute to the directed synthesis of complex rhenium compounds with a certain bioactivity for therapeutic purposes. Synthesized: clusters of Re(III) with amino acids containing aromatic rings (tryptophan, histidine, phenylalanine, tyrosine); compounds of Re(III) with hydroxycarboxylic acids (tartaric, succinic, mandelic, salicylic, etc.); heterocyclic ligands of complex compounds of Re(I). Field of use: C 20.59 Manufacture of other chemical products; C 21.20 Manufacture of pharmaceutical preparations and materials; P 85.42 Higher education; Q 86.90 Other health care activities.
Product Description
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Bielhorodskyi Valerii P.
Bilenka Zhanna V.
Velychko Olena V.
Holichenko Oleksandr A.
Husak Yuliia V.
Zeleniuk Kateryna V.
Kytova Dina Ye.
Lampeka Rostyslav D.
Malook Maksym V.
Ovcharenko Alina O.
Panteleieva Olha S.
Polokhina Kateryna S.
Slipkan Anastasiia V.
Shtemenko Nataliia I.
Shtemenko Oleksandr V.
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2021-04-05
