Registration Number
0221U106176,
0118U007313
, R & D reports
Title
Peculiarities of surgical diseases in children with dysplastic syndrome
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Head
Losiev Oleksandr O,
Registration Date
01-11-2021
Organization
Odessa National Medical University
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The research presents a new scientific solution to the urgent problem of modern medicine - to study the effect of anti-adhesive gel based on sodium hyaluronate on the development of intra-abdominal adhesions in an experiment to develop a method of prevention of pyelooperative adhesions in children with surgical diseases of the abdominal cavity.
Experimental studies were performed on mature Wistar rats, which simulated aseptic and infectious intra-abdominal adhesions and studied the effect of antiadhesive gels on the formation of viscero-parietal adhesions depending on the route of administration and concentration of the active substance. The greatest effectiveness was demonstrated by topical use of a concentrated gel (10 mg / ml) or filling the entire abdominal cavity with a less concentrated gel (5 mg / ml).
Product Description
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Elii Larysa B
Kvashnina Anastasiia A
Losyev Oleksandr O
Melnychenko Maryna H
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2021-11-01