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Information × Registration Number 0222U000501, 0119U103013 , R & D reports Title Optimize topometric preparation for radiation therapy in patients with head and neck cancer popup.stage_title Head Starenkiy Viktor P., Доктор медичних наукSukhina Olena M., Доктор медичних наук Registration Date 11-01-2022 Organization State Organization "Grigoriev Institute for Medical Radiologiy of the National Academy of Medical Sciences of Ukraine" popup.description2 The object of research: is the informativeness of imaging methods in pre-radiation preparation of patients with head and neck cancer. The aim of the study: is to increase the effectiveness of radiation therapy for head and neck cancer by optimizing topometric preparation using modern imaging techniques. Research methods and equipment: X-ray, morphological, clinical-instrumental, statistical, linear accelerator "Clinac-600C", planning system Eclipse 8.9, X-ray computer tomograph "Toshiba Aquilion 64", simulator "Acuity", magnetic resonance imaging, apparatus for ultrasound examination, brachytherapeutic complex "MultiSource", light microscope, device for monitoring the parameters of the radiation beam of a linear accelerator. Theoretical and practical results: evaluated the sensitivity, specificity and accuracy of computed tomography in the topometric preparation of patients with head and neck cancer. MRI topometry has been shown to reduce radiation exposure by 12.5% in the first stage of EBRT compared to classical CT scans. The method of preoperative course of combined radiation therapy with HDR-brachytherapy by dynamic fractionation has been developed. Novelty: the scientific data on radiation toxicity have been supplemented, in particular, the development of grade 3 radiation reactions is 2 times less when planned according to computed tomography data. It has been proven that radiation therapy using HDR brachytherapy according to electron microscopy increases the level of tumor regression by 15%. Effective implementation: reduction of the duration of treatment and the cost of treatment of radiation complications, which averages UAH 4,350 per patient per course of treatment. Field of application: radiation therapy, oncology. Product Description popup.authors Averianova Liliia Oleksandrivna Avrunin Oleh Hryhorovych Akritova Kristina Odiseivna Artiukh Serhii Volodymyrovych Bobrova Vladyslava Maksymivna Bozhok Olha Ivanivna Vasyliev Leonid Leonidovych Hranovska Hanna Ihorivna Hryshchenko Tetiana Petrivna Kiian Tetiana Hryhorivna Kantsedal Olena Mykolaivnа Kyrylova Olena Oleksandrivna Kondrashova Olena Ivanivna Lukashkova Olha Petrivna Maistrenko Ihor Oleksandrovych Makaruk Olena Viktorivna Melnyk Bohdan Ivanovich Nemaltsova Kateryna V. Nosyk Olga Valeriivna Pshyshevska Liudmyla Anatoliivna Roman Nataliia Ivanivna Simbirova Anna Serhiivna Samofalov Ihor Oleksandrovych Svynarenko Anastasiia Andriivna Svynarenko Andrii Viktorovych Teslenko Iryna Mykolaivna popup.nrat_date 2022-03-09 Close