Registration Number
0222U000501,
0119U103013
, R & D reports
Title
Optimize topometric preparation for radiation therapy in patients with head and neck cancer
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Head
Starenkiy Viktor P., Доктор медичних наук
Sukhina Olena M., Доктор медичних наук
Registration Date
11-01-2022
Organization
State Organization "Grigoriev Institute for Medical Radiologiy of the National Academy of Medical Sciences of Ukraine"
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The object of research: is the informativeness of imaging methods in pre-radiation preparation of patients with head and neck cancer. The aim of the study: is to increase the effectiveness of radiation therapy for head and neck cancer by optimizing topometric preparation using modern imaging techniques. Research methods and equipment: X-ray, morphological, clinical-instrumental, statistical, linear accelerator "Clinac-600C", planning system Eclipse 8.9, X-ray computer tomograph "Toshiba Aquilion 64", simulator "Acuity", magnetic resonance imaging, apparatus for ultrasound examination, brachytherapeutic complex "MultiSource", light microscope, device for monitoring the parameters of the radiation beam of a linear accelerator. Theoretical and practical results: evaluated the sensitivity, specificity and accuracy of computed tomography in the topometric preparation of patients with head and neck cancer. MRI topometry has been shown to reduce radiation exposure by 12.5% in the first stage of EBRT compared to classical CT scans. The method of preoperative course of combined radiation therapy with HDR-brachytherapy by dynamic fractionation has been developed. Novelty: the scientific data on radiation toxicity have been supplemented, in particular, the development of grade 3 radiation reactions is 2 times less when planned according to computed tomography data. It has been proven that radiation therapy using HDR brachytherapy according to electron microscopy increases the level of tumor regression by 15%. Effective implementation: reduction of the duration of treatment and the cost of treatment of radiation complications, which averages UAH 4,350 per patient per course of treatment. Field of application: radiation therapy, oncology.
Product Description
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Averianova Liliia Oleksandrivna
Avrunin Oleh Hryhorovych
Akritova Kristina Odiseivna
Artiukh Serhii Volodymyrovych
Bobrova Vladyslava Maksymivna
Bozhok Olha Ivanivna
Vasyliev Leonid Leonidovych
Hranovska Hanna Ihorivna
Hryshchenko Tetiana Petrivna
Kiian Tetiana Hryhorivna
Kantsedal Olena Mykolaivnа
Kyrylova Olena Oleksandrivna
Kondrashova Olena Ivanivna
Lukashkova Olha Petrivna
Maistrenko Ihor Oleksandrovych
Makaruk Olena Viktorivna
Melnyk Bohdan Ivanovich
Nemaltsova Kateryna V.
Nosyk Olga Valeriivna
Pshyshevska Liudmyla Anatoliivna
Roman Nataliia Ivanivna
Simbirova Anna Serhiivna
Samofalov Ihor Oleksandrovych
Svynarenko Anastasiia Andriivna
Svynarenko Andrii Viktorovych
Teslenko Iryna Mykolaivna
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2022-03-09
