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Information × Registration Number 0222U000934, 0121U110361 , R & D reports Title Development of the prototype of medical preparation 'Antithrombotic calix[4]aren C-145' and it's preclinical studies popup.stage_title Head Komisarenko Serhii V., Доктор біологічних наук Registration Date 21-01-2022 Organization Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine popup.description2  We developed a method of detection of C-145 in blood plasma using a functional approach (by the time of coagulation of blood plasma in the APTT test) and using the direct method - high performance liquid chromatography (HPLC). In collaboration with the partner organization, laboratory instructions for the development of a laboratory series of antithrombotic medication C-145 were developed. Performed preclinical trials of antithrombotic drug substance C-145 allow to begin preparation of the clinical phase of trials. Product Description popup.authors Gryshchuk Volodymyr Ivanovych Korolova Dar'ya Sergiivna Lugovska Nataliia Eduardivna Platonov Oleg Maksymovych Platonova Tetyana Mykolayivna Stohnii Evgen Mukolayovych Chernyshenko Volodymyr Olexandrovych Chernyshenko Tamara Martynivna popup.nrat_date 2022-03-09 Close