Registration Number
0222U000934,
0121U110361
, R & D reports
Title
Development of the prototype of medical preparation 'Antithrombotic calix[4]aren C-145' and it's preclinical studies
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Head
Komisarenko Serhii V., Доктор біологічних наук
Registration Date
21-01-2022
Organization
Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine
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We developed a method of detection of C-145 in blood plasma using a functional approach (by the time of coagulation of blood plasma in the APTT test) and using the direct method - high performance liquid chromatography (HPLC). In collaboration with the partner organization, laboratory instructions for the development of a laboratory series of antithrombotic medication C-145 were developed. Performed preclinical trials of antithrombotic drug substance C-145 allow to begin preparation of the clinical phase of trials.
Product Description
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Gryshchuk Volodymyr Ivanovych
Korolova Dar'ya Sergiivna
Lugovska Nataliia Eduardivna
Platonov Oleg Maksymovych
Platonova Tetyana Mykolayivna
Stohnii Evgen Mukolayovych
Chernyshenko Volodymyr Olexandrovych
Chernyshenko Tamara Martynivna
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2022-03-09