Registration Number
0222U002296,
0120U102176
, R & D reports
Title
Fractal dimension and properties of fluid systems relevant to medicine and nuclear technology.
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Head
Bulavin Leonid A., Доктор фізико-математичних наук
Registration Date
11-02-2022
Organization
Taras Shevchenko National University of Kyiv
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Object of research - Mechanisms of formation of fractal aggregates and their influence on the equilibrium and kinetic properties of fluid systems.
The aim of the work is to determine the mechanisms of influence of fractal aggregates on equilibrium and kinetic physical properties of liquid system, on the one hand, and, on the other hand, influence of thermodynamic state of liquid system on fractal cluster formation.
Research methods - optical, low-angle scattering MKRN, MKRR, DMKRN (VSANS), UMKRN (USANS), computer modeling, theoretical and analytical.
According to the ICR data of liquid systems TEOS / water / ethanol revealed an increase in the size of silicate aggregates with increasing relative content of both water and
TEOS, it is established that the reason for this is the conformational diversity of polymer structures formed from hydrolyzed TEOS in basic solutions due to the mechanism of nucleophilic substitution. The structural transition from nanodiamond hydrosols to hydrogels observed with ICRN and ICRP has thixotropy, which is explained on the basis of multilevel fractal aggregation: on three characteristic scales of size, from nanometers to micrometers, different fractal dimensions were observed and therefore different compactness. Stabilization of the micellar system by molecules of water-soluble polymer PEG due to the formation of surfactant-polymer complexes was revealed.
In order to solve the problem of controlled drug delivery using nanoparticles using the methods of ICRP, ICRP and DRS, the mechanism of nanoparticle aggregation was established and the conditions for stabilizing the structure of medicobiological liquid systems containing nanoparticles were determined. A structural model of cluster rearrangement in MRS from branched fractal to elongated chain in the physiological range of temperatures outside and outside it is proposed, taking into account the magnetic dipole-dipole interaction of particles.
Product Description
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Ivanʹkov Oleksandr І.
Alieksieiev Oleksandr M
Artykulnyj Oleksandr P.
Bakumenko Maryna Yu.
Bur'yan Sergiy A.
Gavryushenko Dmytro А.
Holyk Yurij Yo.
Zabashta Yuriy F.
Kovalchuk Valeriy I.
Kondratyuk Tetiana О.
Kosyachkin Egor M.
Kusovkov Yuriy G.
Maliarenko Olena E.
Nikolayenko Tymofiy Yu.
Nagornyj Anatoliy V.
Ogorodnik Kateryna O.
Ostapchenko Sergiy G.
Tomchuk Оleksandr V.
Cherevko Kostyantyn V.
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2022-03-09
