Registration Number
0223U000160,
0120U102092
, R & D reports
Title
Correction of the molecular mechanisms of the animal organism functioning under the influence of ecopathogenic environmental factors and during the development of pathologies.
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Head
Tomchuk Viktor A., Доктор ветеринарних наук
Registration Date
03-01-2023
Organization
National University of Life and Environmental Sciences of Ukraine
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The object of the study is the regulation and correction of the molecular mechanisms of the functioning of the animal organism under the negative influence of ecopathogenic factors of the environment, xenobiotics, infectious agents and the development of animal diseases (entero- and hepatopathologies) in order to ensure food, ecological and biological safety of animals and the population. The purpose of the research is to establish violations of the molecular mechanisms of the functioning of the animal organism under the action of ecopathogenic factors of the environment and the development of pathologies, which is important for the improvement of endoecological technology for carrying out therapeutic and preventive and rehabilitation measures, which involve the use of the corrective effect of a phospholipid-containing drug and a hypoxic-hypercapnic environment to ensure food, ecological and biological safety and preservation of public health. The subject of research is the regulation of membrane-bound metabolic processes; impact on the body of ionizing radiation, xenobiotics (antimicrobial and non-steroidal anti-inflammatory drugs), infectious agent (Esсherichia coli); corrective effectiveness of a phospholipid-containing drug of reparative action and artificial hypobiosis; hepato- and enteropathology of animals. The most sensitive links of metabolism, the state of pro-antioxidant balance and the features of structural and functional changes in the body of mammals under the cytotoxic effect of xenobiotics (different groups of synthetic drugs) were determined; radiation exposure; artificial hypobiosis in combination with experimental escherichia and in the case of an acute stage of babesiosis invasion. The corrective effectiveness of the phospholipid-containing bioadditive "FLP-MD" has been experimentally proven, the use of which accelerates the recovery of animals and prevents the development of complications in the form of toxic hepatitis, fatty hepatosis, nephri
Product Description
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Veselskyi Stanislav Pavlovych
Halat Maryna Vladyslavivna
Gryshchenko Victoria A.
Kladnytska Larysa V
Morosova Valeria S.
Nedosiekov Vitalii Volodymyrovych
Reshetnik Yevdokiia M.
Tsvilikhovskyy Valeriy Ivanovich
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2023-01-03
