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Registration Number

0223U000924, 0122U001592 , R & D reports

Title

A study of the theology of neuropathic pain in patients after spinal nerve injury

Head

Biloshenko Kostiantyn S., Кандидат фізико-математичних наук

Registration Date

21-01-2023

Organization

V.N. Karazin Kharkiv National University

Description

 Methods of modern medicine can already use toxins for selective immunosuppression. But in the case of poisoning by toxins of various nature, the initial diagnosis can often be established by mistake. Quantification of pro- and anti-inflammatory cytokines is rarely performed, such history taking requires a multidisciplinary approach and may take more time. Thus, there is a need for established correlations between the concentration of toxic substances and changes in the cytokine profile in patients with neuropathic pain after spinal cord injury. For this, it is necessary to establish a mutual relationship between the cytokine profile in a person and toxic substances that cause an excess of mediators and as a result pain. For this, the project envisages using the SERS methodology, but creating metasurfaces that enhance the Raman scattering profile of toxic molecules found in the patient's body in extremely low concentrations. All this will contribute to the creation of an effective step-by-step instruction for changes to the actions of clinicians during the diagnosis of patients with unspecified pathology.

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Mits Mykola H.
Riabenko Iuliia A.
Tuz Volodymyr R.