Registration Number
0223U001817,
0120U100031
, R & D reports
Title
The inherited and socially-stress factors in genesis and development of recurrent depressions
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Head
Maruta Nataliia O., Доктор медичних наук
Registration Date
03-02-2023
Organization
State institution "Institute of Neurology, Psychiatry and Narcology, National Academy of Medical Sciences of Ukraine"
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Report on the GDR: 200 pp., 37 tables, 17 figures, 7 appendices, 225 sources.
PATIENTS WITH RECURRENT DEPRESSION, ENVIRONMENTAL FACTORS, HEREDITY, PHARMACOGENETIC MARKERS, CLINICAL-PATHO-PSYCHOLOGICAL FEATURES, PSYCHOPATHOLOGICAL FEATURES, PHARMACOTHERAPY AND PSYCHOTHERAPY.
The object of the study is 225 patients with recurrent depression, who sought help at the Department of Internal Medicine of the National Academy of Medical Sciences of Ukraine and 46 people from the general population, without mental disorders.
The purpose of the research is to determine the influence of hereditary and social stress factors in the genesis of the formation and development of recurrent depressive disorders.
Research methods - clinical-psychopathological, genealogical, determination of pharmacogenetic markers, psychometric - MADRS scale, psychodiagnostics (modified version of the "Antivitality and Vitality" method; multi-level personality questionnaire "Adaptability"; test for stress resistance, diagnostic method of socio-psychological adaptation by K. Rogers - R. Diamond and methods of mathematical statistics.
The results of the NDR made it possible to reveal the peculiarities of the influence of socio-demographic, environmental and genealogical factors and factors of mental trauma on the clinical characteristics and course of recurrent depression depending on the severity of the depressive episode. Identified clinical-psychopathological signs, heredity and features of pharmacogenetic factors in patients with recurrent depression, as well as identifying individual psychological factors allowed to prove their role in the genesis and formation mechanisms of the course of recurrent depressions of different severity. Based on the identified features, a complex system of therapy has been developed.
Product Description
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Atramentova Lyubov Oleksiivna
Gorpinchenko Mykhailo Yuriyovych
Kalenskaya Galina Yuriivna
Kanurniy Ivan Ivanovych
Kiselyova Olga Vasylivna
Kolyadko Svitlana Petrivna
Lapinska Oksana Romanivna
Panko Tamara Vasylivna
Petrenko Oleksandr Leonidovych
Prilepa Valentina Olexandrivna
Semikina Olena Yevgenivna
Tkachenko Olga Viktorivna
Usachova Valentina Volodymyrivna
Utevska Olga Mychalivna
Fedchenko Victoria Yuryivna
Cheredniakova Olena Serhiivna
Yavdak Iryna Oleksandrivna
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2023-02-03
