Search academic texts

Information × Registration Number 0223U003570, 0118U000940 , R & D reports Title The pharmacological study of potential medicinal drugs containing biologically active substances of natural origin popup.stage_title Head Yermolenko Tamara I., Доктор фармацевтичних наук Registration Date 25-05-2023 Organization Kharkiv National Medical University popup.description2  A study was carried out and it was established that the thick extract of carrot roots (GEKM) and the thick extract of parsnip roots (GE-KP) are safe, have an anti-inflammatory effect due to anti-exudative properties, have a significant wound-healing effect and membrane-protective activity, which are one of the links of their wound-healing effect and are promising for further study in order to create new drugs. It is shown that Wundehil ointment exhibits a more pronounced anti-burn effect compared to Spasatel-forte and thiotriazoline 2% ointments, which allows them to be effectively used in the treatment of superficial burn wounds and as reference drugs in the experiment. It has been proven that REPS and 40% alcohol tincture of burdock root exhibit significant diuretic, hypouroco-suric, membrane-stabilizing and hemodilution properties and can be recommended for the creation of new RLZ for the treatment of gout. It has been shown that SNHV has a significant anti-inflammatory and analgesic effect, pronounced gastroprotective properties and does not affect intestinal peristalsis and is promising for further research with the aim of creating a new RLZ for gastroenterology. A more pronounced membrane-protective, anti-inflammatory, analgesic and gastroprotective effect of the drug "Lisichky-drops" compared to the drug "Shiitake-drops" was established. It has been proven that the infusion of Tagetes flowers is safe (LD50 not established) and exhibits significant membrane-protective properties and can be recommended for further pharmacological study. It was shown that corvalol and novo-pasit in the "open field" test suppressed the emotional component and did not affect locomotor and research activity. With long-term immobilization stress, corvalol and novopasit decreased the mass coefficient of the adrenal glands, which indicates a stress-protective effect. Corvalol and novopasit reduced damage to the gastric mucosa against the background of stress due to stress protection. Product Description popup.authors Pautina Olena I. Ruda Natalia G. Chorna Nataliya Stepanivna Shapoval Ol'ga Mykolayivna popup.nrat_date 2023-05-25 Close