Registration Number
0223U004718,
0123U102840
, R & D reports
Title
Novel methods and systems of multifunctional Mueller-matrix polarization and fluorescence tomography of micro and nanostructure of biological crystal networks
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Head
Ushenko Yurii O., Доктор фізико-математичних наук
Registration Date
30-11-2023
Organization
Yuriy Fedkovych Chernivtsi National University
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This project is aimed at the development and experimental testing of the latest methods and systems of multifunctional Müller-matrix fluorescence tomography of the micro- and nanostructure of networks of biological crystals with the aim of solving a current global scientific problem - establishing diagnostic relationships between changes in the optical anisotropy of biological crystals and pathological conditions of human organs. As a result, the experimental relationships between objective parameters and changes in the distributions of linear and circular birefringence and dichroism due to pathological conditions (cancer, inflammation) and degenerative-dystrophic changes (dynamics of necrotic changes) were determined. The established criteria for changes in optical anisotropy at the micro- and nano-levels of the structure of networks of biological crystals are the basis for determining the operational characteristics (sensitivity, specificity, accuracy) of the power of Mueller-matrix fluorescence tomography methods for the differential diagnosis of pathological, inflammatory, and necrotic conditions.
Product Description
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Ivashko Victor V
Gorsky Mykhailo P.
Dubolazov Oleksandr V.
Motrych Artem V
Olar Oleksandr V
Soltys Iryna Vasylivna
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2023-11-30
