Registration Number
0223U005274,
0123U103358
, R & D reports
Title
Novel responsive polymer materials based on structured polysaccharides
popup.stage_title
Head
Samaryk Volodymyr Ya., Доктор хімічних наук
Registration Date
19-12-2023
Organization
Lviv Polytechnic National University
popup.description2
The studies of the formation process of controlled branched and cross-structured polysaccharide macromolecules (using the example of dextrin macromolecules) to create aqueous polymer dispersions with nanometer-sized particles and aqueous suspensions of microhydrogels were described in the research. Such objects are of great practical interest for the creation of drug delivery systems, ensuring the prolonged action, or the use of polymer dispersions as adjuvants for new generations of vaccines. It is also important to give the listed means the properties of theranostics. That is, to ensure the availability of diagnostic and therapeutic functions. Therefore, the main attention in this project was focused on giving polymer dispersions and suspensions of microhydrogels the ability to form a response under the influence of an external factor, in particular, under the influence of UV radiation. For this, a method of grafting chromophoric labels based on fluorescein and pyrene to polysaccharide chains was developed. The influence of these modifications on the course of the stages of branching and cross-structuring of polysaccharide macromolecules, the formation of self-stabilized aqueous dispersions and suspensions was studied. As a result of the research carried out during the implementation of this project, a number of polymer systems for medical and biomedical purposes with fluorescent properties were developed.
Product Description
popup.authors
Bukartyk Natalya
Varvarenko Serhiі
Nosova Nataliya
popup.nrat_date
2023-12-19
