Registration Number
0224U001640,
0123U100225
, R & D reports
Title
Study of inert gases as agents for primary neuroprotection in traumatic and non-traumatic brain injury (clinical and experimental research)
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Head
Zhyliuk Volodymyr I., Доктор медичних наук
Registration Date
26-01-2024
Organization
Dnipro State Medical University
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Conducting an experimental and clinical substantiation of the effectiveness of neuroprotective therapy using inert gases and hydrogen gas in traumatic and non-traumatic brain lesions based on the data obtained regarding their impact on the main molecular and cellular links of pathogenesis and the speed and quality of neurological function recovery. Study of the CNS function and the state of brain metabolism and the dynamics of the neurological status in traumatic or non-traumatic brain lesions in an experiment on rats and in patients in critical conditions. Study of neuroprotective therapy of ischemia-reperfusion injury of the brain using argon and hydrogen gas, changes in neurometabolism indicators and neuron-specific enzymes. With the help of conducting neurophysiological, biochemical, morphological, histoimmunochemical, clinical studies, determine the expediency of using inert gases in the given conditions of the experiment, which contributes to the reduction of neurological deficits and the normalization of disturbed indicators.
Product Description
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Bondarenko Oleksandr O.
Vyshnevskyi Maksym S.
Holubiev Viktor L.
Krishtafor Artur Artur Anatoliiovych
Lievykh Anton Eduardovych
Mamchur Vitaliy
Novytska-Usenko Liudmyla Vasylivna
Oleniuk Diana V.
Pripichenko Liliia O.
Tkachenko Victoriya
Kharchenko Yuliia Valeriivna
Tsarev Olexander V
Shevtsova Alla I.
Sherstiuk Svitlana А.
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2024-01-26