Search academic texts

Information × Registration Number 0224U002585, 0121U108547 , R & D reports Title To substantiate the conditions of immobilization on highly dispersed silica of microorganisms of different taxonomic groups for the creation of probiotic drugs popup.stage_title Head Danylenko Svitlana H., Доктор технічних наук Registration Date 19-02-2024 Organization Institute of Food Resources of the National Academy of Agrarian Sciences of Ukraine popup.description2 The purpose of the research is to investigate the rational conditions of sorption of probiotic cultures of bacteria of different taxonomic groups with preparations of highly dispersed silica for further use in food and pharmaceutical production. Research objects – biological object: probiotic strains from the IPR collection, silica-based preparations: Enterosgel, Sillard P, Toxin.NET. The paper shows for the first time that probiotic bacteria adsorbed on highly dispersed silica preparations had better functional properties in relation to the harsh conditions of the gastrointestinal tract than native cells. The influence of sorption conditions on highly dispersed silica, namely: temperature, the ratio of sorbent based on highly dispersed silica and probiotic culture, mixing conditions and pH of the medium on the effectiveness of adsorption of probiotic microorganisms, the conditions of influence of the protective medium for lyophilization, and experimental technological regulations for the technology of obtaining a complex probiotic were also clarified drug.   Product Description popup.authors Harbar Nadiia I. Danylenko Svitlana H. MARYNCHENKO LOLITA V. Potemska Oksana I. Ushakova Viktoriia V. TSARENOK ANZHELIKA V. popup.nrat_date 2024-02-19 Close