Registration Number
0224U002914,
(0123U100220)
, R & D reports
Title
Polymeric sources of active chlorine for express preparation of antiseptic solutions and water disinfection in military medicine
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Дослідження процесів дезінфекції води хлорактивними полімерами при різних гідродинамічних режимах та відпрацювання методик отримання антимікробних розчинів з заданими фізико-хімічними параметрами з використанням таких полімерів
Head
Stepanskyi Dmytro O., Доктор медичних наук
Registration Date
13-03-2024
Organization
Dnipro State Medical University
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Development of materials, technologies and corresponding devices for their implementation for water disinfection and obtaining highly pure broad-purpose solutions of active chlorine using polymers with immobilized N-chlorosulfonamide groups.
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The use of antimicrobial polymer materials in recent years is considered the most effective method of providing increased resistance to microbial contamination to various plastic and textile products for various purposes, as well as the creation of special medical products with antibacterial, virucidal and fungicidal effects (protective masks and clothing, catheters, implants, etc.) . A separate class of such polymers are halogen- (mostly chlorine-) active materials that can neutralize pathogens directly on their surface, and in some cases - ensure the release of active chlorine (hypochlorous acid in various forms) into the medium treated by them. The advantage of using chlorine-active polymers is the broad spectrum and rate of microbiocidal action of active chlorine, as well as the practical impossibility of developing resistance to it. In addition, in comparison with traditional chlorine-containing disinfectants - aqueous solutions of sodium hypochlorite, organic chloramines, etc. - polymers have much higher stability, can exist in different physical forms (granules, fibers, fabrics, threads, etc.), are more compact, contain less toxic, allergenic and irritating impurities, often do not require special packaging and storage conditions, and some of them can be regenerated. Such properties give them special prospects when used in "field" conditions, for example, in combat zones and emergency situations. The chemical and antimicrobial properties of multifunctional fibrous and granular polymers with immobilized N-chlorosulfonamide groups synthesized by us have proven that upon contact with microbiologically contaminated media, they eliminate an equivalent amount of active chlorine in it, due to which a pronounced microbiocidal effect is achieved. Such properties can be used both for water disinfection and for the quick preparation of chlorine-active solutions, for example, N-chlorotaurine, which can later be used for antiseptic treatment of any surfaces, including op
Product Description
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Ishchenko Oksana V.
Koshova Iryna P.
Kremenchutskyi Hennadii M.
Murashevych Bohdan V.
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2024-03-13
