Registration Number
0224U002951,
0121U110085
, R & D reports
Title
Develop new methods of prevention and treatment of recurrence of breast cancer, aimed at improving the effectiveness of treatment and quality of life.
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Head
Smolanka Ivan I., Доктор медичних наук
Registration Date
18-03-2024
Organization
National Cancer Institute
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The object of research is breast cancer. The purpose of the work is to develop new methods of prevention and treatment of recurrences of breast cancer aimed at improving the effectiveness of treatment and quality of life. Research methods and equipment - clinical, morphological, radiological, statistical; "Simens" mammograph, "Aloka" ultrasound device, "Philips BV Pulsera" hagiography device, "Magniterm" device. An analysis of the immediate results of treatment of patients with RGZ with a high risk of relapse according to the developed and standard methods was carried out. The analysis of the results of combined treatment in patients with a high risk of relapse in three groups of patients (a group of patients who underwent oncoplastic and reconstructive-restorative operations; a group of patients with modified PCT and a group of patients with traditional treatment) was carried out. The results of treatment in the studied groups were evaluated. The sequence of stages of treatment for the group of patients at risk of relapse was determined. A comparative analysis of the obtained results indicates a probable advantage of the methods of modified chemotherapy and oncoplastic surgery compared to standard methods of combined treatment. In the experimental group (modified PCT), an increase in the number of cases of partial and complete tumor regression was noted (56.7% vs. 46.7% and 43.7%). In the experimental groups (modified PCT and oncoplastic operations) there is a tendency to increase three-year recurrence-free survival 81.7 ± 4.8 and 83.3 ± 3.9% against 72.0%). In the experimental groups (modified PCT and oncoplastic operations), the quality of life of patients improved by 85 ± 3.6%, 98 ± 4.2% versus 83 ± 3.2% with traditional treatment.
Product Description
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Ivankova Oksana M.
Dosenko Iryna V.
Liashenko Andrii O.
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2024-03-18
